Hello, thank you for reaching out to Microsoft Q&A.
If you already have any third-party antivirus software such as McAfee, Norton, etc. installed on your computer, you may not be able to run a Windows Security scan. These apps can take over and block the Virus & threat protection settings in Windows Security. If you have any of these apps installed, uninstall them first, then run a full system scan using Microsoft Defender. Here's how:
- Go to Start > Settings > Privacy & security > Windows Security > Virus & threat protection.
- To perform a quick scan, click Quick scan on the main screen.
- To run other types of scans, select Scan options.
- You can choose between Quick scan, Full scan, Custom scan, and Microsoft Defender Offline scan.
- Once the scan is complete, Windows will show the scan results and notify you if any threats are found.
For reference, see
Stay Protected With the Windows Security App